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Why Aren’t We Talking About Depression and Menopause?

Breaking the silence on an overlooked symptom of menopause: depression
Featuring
WRITTEN BY:
Team Biolae
MEDICALLY REVIEWED BY:
Dr. Madison Davies
WRITTEN BY:
Team Biolae
MEDICALLY REVIEWED BY:
Dr. Madison Davies
THE BIG PICTURE
Menopause is inevitable. Navigating it blind is not.
Perimenopause starts years before your last period, with hormone fluctuations triggering up to 50 symptoms like hot flushes, mood swings, sleep issues, and brain fog.
Menopause itself is a one-day milestone (12 months without a period) — but the effects can linger, often lasting 4–10+ years.
Postmenopause brings lower hormone levels and new health risks like osteoporosis, cardiovascular concerns, and vaginal changes.
This guide is here to help you cut through the noise. It’s your resource for trustworthy, fact-based support as your body transitions through the stages of menopause.

Bookmark it, share it, come back when you need clarity.
Explore our range of science-backed, natural treatments for menopause symptoms.
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Menopause is often discussed in terms of hot flushes, night sweats, or changes in sleep quality, but what’s less talked about is its profound impact on mental health. For many women, the menopausal transition brings emotional upheaval, with depression being one of the most overlooked symptoms. Research shows that women in perimenopause are 40% more likely to experience depression compared to premenopausal women (1). Yet, the conversation around this remains surprisingly quiet.

It’s time to break that silence.

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01

Menopause and Mental Health

The menopause transition—which includes perimenopause, menopause, and postmenopause—isn’t just a physical experience. Hormonal changes during this time affect every aspect of life, especially mental and emotional health. As estrogen and progesterone levels shift, they disrupt brain chemistry in ways that can lead to mood changes, including depression.

For many women, menopause coincides with a particularly stressful chapter of life. Juggling careers, raising children, or dealing with aging parents—all of this can compound the emotional toll. The pressure to keep everything running smoothly often leaves little room for self-care, and the creeping sense of depression can easily blend into the background of life’s many demands.

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02

Hormonal Fluctuations and Depression

Estrogen isn’t just important for regulating your menstrual cycle; it’s a key player in managing mood. As estrogen levels decline during menopause, so does your brain’s ability to regulate emotions, leaving you more vulnerable to depressive symptoms. If you’ve previously struggled with mood symptoms of anxiety or depression, the hormonal imbalance of menopause can amplify these feelings, making it harder to manage your emotional well-being.

But even for women who’ve never experienced mental health symptoms, menopause can be a tipping point. The hormonal shifts often leave women feeling emotionally adrift, contributing to mood swings, irritability, and in some cases, more serious forms of depression.

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03

How to Identify Depression During Menopause

It’s not always easy to tell when depression is creeping in. The emotional symptoms of menopause often overlap with other menopause symptoms, like irritability or fatigue, making it hard to pinpoint what’s really going on. However, persistent sadness, loss of interest in activities that used to bring you joy, insomnia and a sense of hopelessness are key indicators that something deeper is at play.

Women going through menopause may also experience anxiety, difficulty concentrating, or a general sense of overwhelm. These are more than just “bad days” or fleeting mood changes. When these feelings become persistent and start interfering with daily life, it may be time to consider that depression is at the root.

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04

Major Depressive Disorder vs. Menopausal Depression

Depression during menopause can range from mild to severe. While some women experience brief periods of low mood, others may develop Major Depressive Disorder (MDD), a clinical form of depression that can have a significant impact on daily life. Women with major depression may struggle with constant feelings of low mood, loss of interest in nearly all activities, and changes in weight, sleep, or energy levels.

If you find that these symptoms are persistent or worsening, it’s essential to seek professional help. Major depression is a serious condition, but with a diagnosis and the right treatment, it’s manageable.

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05

What Increases the Risk of Depression During Menopause?

Several factors can increase the risk of depression during menopause. These include emotional challenges, such as a history of depression, anxiety disorders, or stressful life events like divorce or the loss of a loved one. Sleep disturbances—a common symptom of menopause—can also contribute to depressive symptoms.

If you’ve previously experienced postpartum depression, you may be at a higher risk for developing depression during menopause. This connection highlights the biological and psychological risk factors at play throughout a woman’s reproductive life. Recognising these risks early on can help you get ahead of the symptoms and find the support you need.

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06

Managing Mental Health During Menopause

Managing your mental health during menopause isn’t a one-size-fits-all solution. It requires a multi-faceted approach that combines medical care, lifestyle changes, and emotional support.

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07

When to See a Healthcare Provider

If you’re noticing depressive symptoms—whether mild or severe—talk to your doctor or healthcare provider. They can assess your symptoms and recommend a treatment plan that’s right for you. This could include hormone therapy, antidepressants, or a combination of treatments depending on your specific needs.

If you are in Australia and need help now, call:

  • Lifeline – 13 11 14
  • Beyond Blue – 1300 224 636

For other regions, seek support from your local hotline.

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08

Hormone Therapy, Antidepressants and CBT

For women experiencing severe depressive symptoms, hormonal therapy can help restore the balance of estrogen in the body and alleviate mood-related symptoms. For others, antidepressants may be a better option, particularly if Major Depressive Disorder or a long history of anxiety is at play. Cognitive Behavioural Therapy (CBT) is another highly effective treatment for managing emotional fluctuations, offering practical strategies to reframe negative thinking and cope with stress.

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09

Natural Alternatives and Lifestyle Changes

If you prefer natural approaches, lifestyle changes can make a significant difference to depressed mood. Regular exercise, a balanced diet, and ensuring you get enough sleep are crucial to stabilising mood. Nutritional supplements like omega-3 fatty acids, magnesium, and vitamin D can also support emotional well-being, helping to reduce the intensity of depressive symptoms.

Incorporating mindfulness practices like meditation or deep breathing can also be transformative. These tools help calm the mind and build emotional resilience during what can be a turbulent time.

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10

Breaking the Stigma Around Menopause and Mental Health

One of the biggest barriers to managing mental health issues during menopause is the lingering stigma surrounding both menopause and depression. Too often, women are expected to soldier through, to “just get over it” when, in reality, the emotional challenges of menopause deserve real attention. It’s time to normalise conversations about menopause and mental health, breaking down the shame that holds so many women back from seeking help.

Depression is not a weakness, nor is it something you have to live with in silence. By recognising the signs early, seeking support from a trusted health professional, and adopting strategies that prioritise your mental health, you can navigate menopause with resilience and confidence. Remember, you don’t have to go through this alone. Prioritising your mental health during menopause is not just important—it’s essential.

EDITORIAL STANDARDS
Biolae’s commitment to informed support
At Biolae, we’re here to support women through every stage of hormonal change with science-backed care, no judgment, and no guesswork. We believe education plays a powerful role in helping you understand what’s happening in your body and how to care for it.

Our content is guided by a commitment to clarity, trust, and evidence. Everything we share is reviewed for accuracy and informed by the latest clinical research and expert insight — so you can feel confident in every step you take with us.
Learn more about how we create content →
References:
  1. Freeman, E. W., et al. “Hormones and mood during perimenopause.” Journal of Affective Disorders, vol. 83, no. 2-3, 2004, pp. 259-267.
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